Global cases of HYPERURICEMIA exceed 41 million with an ‘alarming rate’ of increased burden Hyperuricemia occurs due to high uric acid levels in the blood. Today’s sedentary lifestyle in Asian Countries has been the number one factor responsible for a high number of cases. Hyperuricemia can also be caused because of increased alcohol consumption, high levels of meat ingestion or high levels of seafood ingestion. There is a strong association that links Hyperuricemia directly to Cardiovascular diseases therefore increased uric acid levels should be constantly monitored and controlled in the general population with the help of URIPLEX DROPS. Indications • Uriplex Drops effectively relieve Symptoms associated with hyperuricemia (High level of uric acid) like severe pain/stiffness/ redness/ swelling in the joints etc. Ingredients • Berberis Vulgaris 3X• Lycopodium Clavatum 3X• Urtica Urens• Taraxacum 3X Symptoms or causes • Uriplex drop is a safe, side-effect-free medicinal solution for hyperuricemia. • Hyperuricemia can be defined as uric acid elevation level in blood due to urate overproduction and decreased uric acid excretion. • Urate overproduction may occur because of purine-rich diet, error of purine metabolism, and certain disease conditions like hemolysis, rhabdomyolysis, tumor lysis, etc. • Acute or chronic kidney disease can reduce uric acid excretion. [1]• Gout is a very classic condition associated with hyperuricemia. [1] • The acute gouty attack represents severely inflamed and very painful joint/s that peaks within hours. • Inflammation is followed by hotness, redness, tenderness, swelling, and loss of function.• Knees and ankles, skin signs are the joints usually get affected with intense pain and swelling. [2] Mechanism of action of Uriplex drops • Berberis vulgaris, Lycopodium clavatum, Urtica Urens, Taraxacum Officinale are four medicinal plant extracts that are blended to formulate Uriplex drop. • Xanthine oxidase plays a vital role in uric acid formation. [3]• The primary mechanism of action of Uriplex drop against hyperuricemia is inhibiting the xanthine oxidase (XO) enzyme. • Berberis vulgaris extract can inhibit the xanthine oxidase enzyme and act as an anti-hyperuricemia effect. • The pre-clinical trial result reported the efficacy of Berberis vulgaris against hyperuricemia or gout. [4]• Uriplex drop containing Lycopodium clavatum can slow down protein metabolism and provide a remedial benefit against gout. • Lycopodium clavatum ingredient is also improving uric acid excretion by preventing kidney stone production. [5] • Lycopodium clavatum also acts as a xanthine oxidase inhibitor to treat gout. [6]• Urtica Urens has potential anti-inflammatory effect and anti-arthritis effect. In Homoeopathy, Urtica Urens are widely used for the treatment of uric acid-related problems such as gout, uric acid diathesis, and joint pain. [7] • Taraxacum Officinale can eliminate uric acid by increasing urine output. [8] Taraxacum Officinale also has kidney protective benefits. [9] Dosage • 10 drops in some water, 3 times a day 1 hour before or after meals or as prescribed by the physician.
